PIRIA, R. (RAFFAELE). - THE FIRST PREPARATION OF SALICYLIC ACID THE MAIN COMPONENT OF ASPIRIN.

Recherches sur la Salicine et les Produits qui en dérivent.

(Paris, Crochard et Comp., 1838). No wrappers. In 'Annales de Chimie et de Physique', 2e series, Volume 69, third- issue, pp. 225-352 (entire issue offered). Piria's paper: pp. 281-325.

First appearance of the paper in which Piria relates how he for the first time prepared Salicylic Acid in its pure state. Salicylic acid occurs naturally in the bark of plants such as willow trees and is used to create aspirin and skin care products. Salicylic acid, whether used internally or externally, is associated with some potential hazards. Henri Leroux had extracted salicin, in crystalline form for the first time, but Piria was the first to extract its pure form.

Garrison & Morton: No 1857 (referring to the same paper published a year later in Comptes Rendues).

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