PASTEUR, (LOUIS), (CHARLES) CHAMBERLAND et (PIERRE PAUL EMILE) ROUX. - A FOUNDING PAPER IN IMMUNOLOGY.

Sur l'étiologie du charbon.

(Paris, Gauthier-Villars), 1880. 4to. No wrappers. In: "Comptes Rendus Hebdomadaires des Séances de L'Academie des Sciences", Tome 91, No 2. Pp. (71-) 138. (Entire issue offered). The paper: pp. 86-94.

First appearance of a classic paper in immunology in which the authors recorded the use of attenuated bacterial viruse for therapeutic purposes based on the theory that bacterial virulence could be attenuated by culture in vitro and used as vaccines. Proposed that live attenuated microbes produced immunity by depleting host of vital trace nutrients and used to make chicken cholera and anthrax "vaccines".

Garrison & Morton: 5169.

Order-nr.: 48138