THE DISCOVERY OF VITAMIN E

EVANS, HERBERT MCLEAN (+) KATHRINE SCOTT BISHOP.

On the existence of a hitherto unrecognized dietary factor essential for reproduction.

New York, The Science Press, 1922. Royal8vo. Bound in contemporary full cloth with gilt lettering to spine. In "Science", New Series, Volume LVI [56], July - December, 1922 Entire volume offered. Library stamp to front free end paper, Soiling to extremities and back board loose, internally fine and clean. Pp. 650-51. [Entire volume: VIII, 760 pp.].

First appearance of Evans and Bishop seminal paper in which they discovered Vitamin E.
In 1922 along with Katharine Scott Bishop, during feeding experiments on rats, Evans discovered that rats did not reproduce when fed a semi-synthetic purified diet in which lard was the sole source of fat. They observed that a 'substance X' in lipid extracts of various grains would correct the fertility defect.
It was first isolated in a pure form by Gladys Anderson Emerson in 1935 at the University of California, Berkeley.

Garrison & Morton 1055

Order-nr.: 49464